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Prostate cancer cases
Case 1: Malignant prostate pathology
Name: Eber Paiva
Age: 67 years old
Country: Uruguay
Reason of consultation:
10/5/2001 Consults because of polaquiury and disury. Has UAR done
which makes him been catheterized. He is treated with pelvic anti-
inflammatories and does not improve. This symptomatology was present
since six months ago. The episode of the UAR motivated his consultation.
Personal antecedents: No personal antecedents to remark.
Family antecedents: Mother deceased because of a rectum AC.
Present disease’s antecedents:
He begins six months ago with polaquiury and disury which needs
the mentioned treatment to be performed. Rectum tactum performed,
prostate compatible with a IV grade hypertrophy. (see page 17).
Biopsy by trans-rectum ultrasonography that shows well differentiated
prostate adenocarcinoma. Gleason 5, PSA 14,94 (see page 18).
GREEN SAP initiated on November 3rd., 2001, 40 drops 3 times per day.
PSA after 30 days: 8,21.
11/23/2001: Computerized tomography (see page 23): Prostate size
very increased and its density is heterogenic, which can correspond
to a necrosis in its interior. It disfigures the blade’s floor
but does not seem to infiltrate it.
It is decided to increase the medicament to 40 drops 4 times per
day. He improves the urination disorders (urination stinging) and
testicle pain.
Disease evolution: On the 01/06/2002 has PSA tested which result
is: 6.74 ng/ml. (see page 25). On the 08/22/2002 Total PSA 0.83
ng/ml. (see page 27). It is remarkable that the patient also received,
as we advised conventional therapy, hormonal and radiant, being
at the present moment in clinic cure following with the ingestion
of our medication.
Released patient, ingests the medicament for one month yearly in
a dosage of 30 drops per day.
Conclusions: 67 years old, with no personal antecedents to mark,
suffers an urine acute retention. The biopsy by trans-rectal ultrasonography
shows a Prostate Adenocarcinoma well differentiated Gleason 5, PSA
14.94. GREEN SAP treatment is initiated on November 3rd., 2001, 40 drops
3 times per day. He quickly improves his urinary disorders and testicle
pain that grieved him.
He reaches clinic cure and release thanks to the use of GREEN SAP, which
has an acknowledged efficacy in Prostate cancer.
GREEN SAP is a medicament of proved efficacy in this pathology, demonstrated
along the years and the empiric experience. It is evident that GREEN SAP
avoided more significant damages in the patient and we can say that
it is a medicament for which this patient lives thankful for having
eliminated his illness.
Case 2: Malignant prostate pathology: Mr. Héctor
Tanco.
Name: Héctor Tanco
Age: 66 years old
Country: Argentina
Reason of consultation:
12/26/2000 Consults because of polaquiury with no other symptoms.
Normal urine.
Personal antecedents: Hypertension, treated with hyposodic diet
although he does not attach to it regularly.
Smoker until 30 years ago. No alcohol. Apendicectomized and amigdalectomized,
asthma until 22 years old.
Family antecedents: None to remark.
Present disease antecedents:
Begins with polaquiury. Studied with PSA showed figures of 84.5
on the 03/05/2001 which motivated a more exhausting study (see page
35).
04/04/2001- Has ultrasonography done which show images compatible
with prostate of 38 mm. x 36 mm. and an approximate weight of 28
g., slightly post-urinary residue with no pathological significance,
blade wall of normal thickness, with no endoluminal projections,
joining free blade-urethers. Bilateral renal ultrasonography: both
kidneys are of normal shape and size, with parenquimo-sinusal relation
conserved. They are not observed neither signs of hydronefrosis
nor images that could correspond to lithyasis (see page 33).
Prostate Biopsy Punction under trans-rectal ultrasonographic control.
Images compatibles with: Prostate of 38x41x31 mm. which shows an
approximately weight of 34 g. The specific prostate antigen for
that weight would be 4 ng/ml. Cystic image in retro-uretheral central
zone, seminal vesicles symmetric (see page 43).
Pathological Anatomy: showed a well differentiated Prostate Adenocarcinoma.
Gleason Score 5 (3+2). It is a bilateral carcinoma, the compromise
is similar in both sides and of a 50 %. Date of the result: 05/15/2001.
Total bone centellography: Date 06/06/2001 in the bone scan performed
no pathologic hyper-concentration areas of the isotope are seen
(see page 47).
Abdominal and pelvic Computerized Axial Tomography: The liver conserves
its habitual morphology and density, its structure is homogeneous,
there is no dilatation of the bilious way, the bilious vesicle content
is homogeneous by this method. Spleen, pancreas, kidneys and adrenal
conserved. At the pelvic area an increased size of the prostate
is observed with of the blade floor, the blade shows its walls slightly
thickened. No lymph nodes retro peritoneal iliac or inguinal are
observed.
Disease evolution: A treatment with gosereline, 3,6 injectable,
monthly, is installed, and bicalutamide 50 mg. per day. As a definitive
pretreatment is installed B.A.T.
We indicate 50 drops of the medicament, sublingually, every 6 hours.
06/06/2001 A bone centellography is done, showing that in the bone
scan performed no areas of pathological hyper-concentration of the
isotope are seen.
04/03/2002 Asymptomatic, increased to 60 drops every 6 hours.
Normalization of his free PSA.
Patient who begins his disease in stage T 2c N0 M0. He took the
medicament during a year, at the present moment he is at clinic
cure, taking 30 drops per day during one month, one month per year.
Patient on release.
66 years old, hypertension, treated with hypo-sodic diet, carrying
a prostate differentiated adenocarcinoma, Gleason Score 5 (3+2),
with similar compromise of both sides of a 50 % (05/15/2001).
Treated with gosereline 3,6 injectable during a month and with bicalutamide
50 mg. per day. A total androgenic blockade is performed, definitive
pretreatment.
He receives the medicament 50 drops sublingually every 6 hours;
he reaches the cure due to GREEN SAP which was the medicament he most received.
There is normalization of the biochemical parameters which are beneath
normal limits.
The patient leads a life with an excellent quality thanks to the
medicament.
GREEN SAP has an excellent action against prostate cancer and has achieved
that this patient leads a complete life and has eliminated his neoplasy
thanks to this medicament. GREEN SAP has returned to him total functionality
and changed his life, due to its efficacy empirically proved and
of first level in prostate cancer.
Case 3: Malignant prostate pathology: Mr. Raúl
Smith.
Name: Raúl Smith Belgrave
Age: 77 years old
Country: Cuba
Reason of consultation:
Night urine and weak urine flow.
Personal antecedents:
Mesenteric thrombosis in January,1995. He went under surgery and
is evolutioning without difficulty.
Family antecedents: With no antecedents to remark.
Present Disease Antecedents:
Because of the night urine and weak urine flow was attended by an
urologist who found at the rectal digital exam a prostate size increased
and hardened of woody consistence, therefore indicating the following
complementary exams which showed the following results:
01/11/2002: Hemoglobin 134 g/l, Eritro 14 mm/h, Creatinine 98 mmol/l.
Prostate ultrasonography: Bladder almost empty, anyway prostate
size globally increased and heterogeneous, which measures 55x41.
Superior hemi-abdomen ultrasonography: fat liver, no nodular lesion,
no other alterations.
Bone gammagraphy: Nuclear bone scan where increased accumulation
of the radio-pharmaco can be seen in the lumbar vertebral column
(L5) and reduced accumulation in both sacroiliac joints.
Prostate biopsy 01/11/2002: Moderately differentiated prostate adenocarcinoma,
Gleason 6, PSA 88,1 ng/l. It was concluded that the patient presents
a moderately differentiated prostate adenocarcinoma not metastasic
and he was indicated to begin with Androcur 2 tablets per day. The
month after having begun the treatment PSA is repeated 02/12/2002:
from 88 ng/l to 21,4 ng/l.
Besides the patient experiments a notable improvement related to
the night urine previously mentioned.
Disease evolution:
It was not possible to follow through the PSA as there are no reactives
in the country. But the imagenologic studies were repeated on the
07/04/2002 and the gammagraphy showed the following inform:
Nuclear bone scan shows larger accumulation of the radio-pharmaco
on the fifth lumbar vertebra subjective of an increased osteoblastic
activity at that level.
It is suggested a conventional radiological study to discard bone
degenerative process, in the rest of the skeleton no other pathological
captures can be visualized.
Now the patient refers to present only pain in the hip joint.
12/09/2003 Another PSA is done and is of 12 ng/l and the hip joint
pain has frankly improved, he goes on with the treatment with the
medicament in a dosage of 40 drops 3 times per day.
On the 02/26/2003 another PSA is done which is of 7,4 ng/l, the
night urine has improved remarkably, he is in a good general state
of health. He did not have loss of weight. He keeps a good appetite.
03/07/2003 He is reevaluated by oncology and urology and is reported
as clinically cured.
All the complementary exams are within normal parameters. (see Some
e-mails received page 159).
Patient on release clinically cured.
Conclusions: Patient of 77 years old proceeding from Cuba, with
personal antecedents of mesenteric thrombosis in January 1995, who
consults due to a low urinary syndrome, being explored with rectal
tactum which showed prostate increased in size, hardened, of woody
consistence. Prostate ultrasonography, bladder almost empty, though
prostate globally increased in size, and heterogeneous, which measures
55 mm x 41 mm. By ultrasonography there is either no liver compromise
nor other abdominal alterations.
Bone centellography with increased accumulation of the radio-pharmac
in lumbar vertebral column (L5) and reduction of it in both sacroiliac
joints. The 01/11/2002 biopsy showed Moderately Differentiated Prostate
Adenocarcinoma, Gleason 6, PSA 88,1 ng/l. He was indicated Androcur,
2 tablets per day and the PSA lows to 21,4 ng/l.
On the 12/09/2003: PSA in 12 ng/l, frank hip joint pain improvement,
receiving a dosage of 40 drops 3 times per day. Patient on urology
and oncology release, with last PSA of 7,4 ng/l. Good general state,
no weight loss and good appetite. All the complementary exams are
within normal parameters. There is no doubt that the benefic effect
of GREEN SAP on the prostate cancer, has manifested totally, conducting
to the clinic cure of the patient, as well as his doctor daughter
tells us by e-mail.
This patient achieved the cure of his pathology thanks to the use
of GREEN SAP, that has a proven first level efficacy in prostate cancers,
as well as in lots of others. It supports this testimony the fact
that this patient’s daughter is a colleague who worked in
the National Oncology Institute of Cuba and actually is working
in Luanda – Angola. Once again GREEN SAP contributes to the eradication
of a malignant pathology and to the patient having a worthy life
and disease free.
Case 4: Glandular hyperplasia with atypical focuses
with PIN III
Name: Luis Mohana
Age: 72 years old
Country: Argentina
Reason of consultation:
05/02/2002 The patient’s wife consults, he presents prostate
tumor.
Personal antecedents:
No personal antecedents to remark.
Family antecedents: None to remark.
Present disease antecedents:
Treated due to bladder polyps, with multiple explorations. In one
of them a prostate increased in size is discovered, having the patient
a normal PSA. In the first Pathological Anatomy can be seen various
fragments of prostate tissue with glandular hyperplasia, ectasy,
chronic inflammation and multiple areas of PIN III with acinar hyperplasia,
(see page 57). Results: low molecular weight queratine positive
95 % and (++). High molecular weight queratine positive in the area
of atypical proliferation. PIN III (Diagnosis: glandular hyperplasia
with micro-areas of PIN III).
Note: No total loss of basal layer is observed in these areas.
It is indicated control and treatment in Oncology Urology center
in Buenos Aires. A biopsy is solicited 6 months from now on and
PSA 3 months from now on. It is indicated to begin with the medicament
with 30 drops 4 times per day sublingually.
Disease evolution:
06/05/2002 – Consults again with his wife. He refers asymptomatic,
has a PSA to be done the 07/03/2002. The PSA levels are on increase
but always within normal limits.
03/07/2002 PSA – 2,1 ng/ml
03/26/2002 PSA – 2,54 ng/ml
We keep in touch by e-mail or telephone. He accomplishes the treatment
with the medicament precisely and the process keeps localized. As
we do not see the patient we cannot have the perception that gives
clinic exploration, anyway, at the present moment, the patient is
within normal parameters.
07/10/2002 – Telephone communication with the patient who
refers his 07/03/2002 PSA as of 3.09 ng/ml, that he is asymptomatic
and his general state is good. He keeps on receiving 30 drops 4
times per day sublingually; we increase the dosage to 45 drops 4
times per day due to the slight increase of the PSA.
08/07/2002 A telephone communication with the patient was made,
where he refers being asymptomatic, with good spirit, and performing
all his daily activities. He considers that the intake of the drops
has benefited him remarkably, opinion we share. Next control in
March, 2003. Clinically stable patient. He goes on with the medicament
with 45 drops 4 times per day.
03/25/2003 Telephone communication with the patient in what he communicates
us he is in excellent state of health performing his daily activities
and with no kind of problem. He send us via fax the last PSA made
on the 03/14/2003 with a value of 3,56 ng/ml. (see page 59). Also
he sends a pelvic ultrasonography with normal results (see page
60). Patient on release, at present on clinic cure. It is indicated
a maintenance dosage of 30 drops per day during a month, once a
year.
Conclusions: Patient with malignant prostate pathology of 72 years
old proceeding from Argentina, consulting his wife and referring
to us a prostate tumoration. Treated due to bladder polyps, in one
of them is discovered the prostate was increased in size, having
a normal PSA.
The pathological anatomy shows glandular hyperplasia with micro-areas
of PIN III, and begins treatment with the medicament on May 3rd.,
2002.
Beginning with 30 drops, 4 times per day sublingually. Evolution
towards an improvement, keeping always the PSA within normal values.
Effect we attribute to the GREEN SAP. Patient who at present we can consider
cured (not with the criteria of 5 years, international criteria)
thanks to the use of GREEN SAP, which once again has shown its nobility
as an anti-neoplasic medicament allowing the patient to be in a
good state of health performing the daily activities that any person
can do.
Case 5: Malignant prostate pathology
Name: Pablo Cordero
Age: 88 years old
Country: Panama
Reason of consultation:
05/25/2002 Acute urine retention
Personal Antecedents:
Gonartritis; hypo-acusia.
Family antecedents: None to remark.
Present disease antecedents:
In January, 2002, due to an acute urine retention, after being examined
he was given the diagnosis of prostate cancer, he had a bladder
endoscopy made towards the end of March, resulting positive and
was indicated Flutamide one tablet 3 times per day. He was suggested
an orchectomy, but his family prefers alternative therapy. He looses
weight. Anemic, with no pelvic pain, with bladder catheter. He underwent
a prostate biopsy punction. Anatomy pathology Diagnosis: A. Prostate,
right lobe (biopsy), moderately differentiated adenocarcinoma, Gleason
3+4=7 which compromises approximately 30 % of the sample, with no
peri-neural invasion.
There’s a PIN III area of high grade, areas of lympho-vascular
permeation are observed. B. Prostate, left lobe (biopsy), moderately
differentiated adenocarcinoma Gleason 3+4=7 which compromises approximately
20 % of the sample.
No peri-neural or vascular invasion is observed.
A month later bone centellography shows compromise, not defining
in which bone.
Disease evolution: They decide to use our medicament.
The patient feels well and the catheter was retired. In the 4th.
month of treatment with the medicament he is urinating normally.
On February 11th., 2003, underwent a surgery due to intestinal occlusion
caused by adherences of an old appendicitis surgery. He was grave
and stayed in hospital for 36 days.
Also due to a pneumonia because of a hospital bacteria, but he is
recovering satisfactorily.
He had a rectal exam done and a pelvic and abdominal computerized
tomography. In the rectal exam a prostate increased in size but
soft was found, as a bubble and not woody. He did not show pain
at the tactum, the CAT showed a somehow big prostate. The surgeon
informed that in the operation area the intestines were metastases
free, only some necrosis of the thin intestine due to adherence
was found.
He changes doctor and consults a urology oncologist, who did not
know his case and found a prostate with the size of a plump.
The prostate was found to be of soft consistence as rubber and had
a little protuberance also soft. He was surprised by the fact that
previously he had been diagnosed as advanced prostate cancer. The
doctor saw the biopsy and confessed that if it wasn’t for
it he wouldn’t have believed it was the same patient.
A bottle of the medicament he was taking is shown to the doctor.
He concluded that this medicament, which was the only thing he was
taking, must have improved his cancer. Anyway he ordered some laboratory
exams and “X” rays, he recommended to go on taking the
medicament.
The patient is asymptomatic, in clinic cure and on release. (see
Some E-mails received, page 159).
Conclusions on anti-tumor GREEN SAP action on malignant prostate neoplasies.
Evidently, as for the collected experience, a benefic effect of
GREEN SAP on prostate neoplasies is found, which is demonstrated by normalizing
or reducing the PSA, causing a loss of size of the tumors evident
either by rectal tactum or by trans-rectal ultrasonographies explorations,
as well as on its consistence which goes from rocky to woody and
from woody to a normal prostate consistence. The particular histological
structure of the prostate can be in the genesis of this interaction
which is hurtful to the tumor. Probably by a antiangiogenic mechanism
the neo-vascularization of the tumor is prevented, depriving it
of essential nourishing factors for its development. This development
has lost control, the cells have lost contact inhibition to proliferate.
GREEN SAP would act too at tumor cell’s nucleus level, affecting
its DNA and preventing the malignant cell’s proliferation;
altering the order of the DNA bases and provoking a molecular “disorder” which would lead to the apoptosis, that is tumor cell death not
only at the moment of GREEN SAP action but also afterwards, generating
a chain effect that evolutes to the tumor death induced by GREEN SAP.
This is maybe the reason why we find samples of prostatectomies
with important intra-tumor necrosis and hemorrhages in their way
to resolve or organizing; this observation would not correspond
so much with the conventional hormonal treatment generally used.
It was also observed that GREEN SAP; prevents the creation of new tumor
clones that escape to the body’s control and provoke early
metastasis moreover on the bone substance, prostate metastases have
avidity for bones.
Therefore GREEN SAP has a protective action on the bones preventing this
body sector’s colonization by the disease, we observed osteoblastic
lesions treated with GREEN SAP that set back and are eliminated by the
organic depurator systems, provoking a removal and mobilization
of the accumulated substance in the skeleton or particular areas
of it.
The bone centellography exploration allows to appreciate the differences
among treatments before and after the GREEN SAP.
The hormonal traditional therapy has the risk of provoking thrombotic
pathology.
This is another effect we see that does not occur with GREEN SAP, when
a conventional treatment plus GREEN SAP is faced, what leads to the patient’s
benefit as it frees him of thrombosis of the lower limbs and other
economy’s areas.
Many times this can be the event that provokes a lung thrombo-embolism,
and this can lead to a very characteristic episode which can lead
towards the patient’s death. Knowing the fact that lung thrombo-embolism
is diagnosed by perfusion-inhalation centellography, in order to
appreciate the lung area that ventilates and therefore the affected
one, we can affirm that in conventional-GREEN SAP mixed treatments, we
did not observed it so it does not occur in our casuistic.
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